Pediatric Compounding

Taking care and giving medication to sick children can be challenging at times. They may resist taking medication, dislike the taste or texture, have difficulty swallowing solid dosage forms, and are afraid of injections. Also, variations in body size, weight, allergies and drug tolerance are added factors relating to this problem. In pediatrics, commercial medications can be limiting. Most drugs are not labeled for pediatric populations, and usually not available in suitable dosage forms.

Compounding can help solve these problems by providing appropriate alternatives. Pharmacists can compound oral medications into pleasantly flavored suspensions, solutions, concentrates or lozenges, in colors enticing to children. A palatable formulation is more likely to improve compliance and minimize spillage or waste during administration. Drugs can be compounded into transdermal gels which can be easily applied to an appropriate site for absorption through the skin.

Professional compounding is not merely diluting medications or mixing powders with bases. Physical and chemical properties of each ingredient should be considered to prepare efficient and safe customized medication with the desired properties. The efficacy of any compounded drug is influenced by the technique and equipment used in preparation, purity and quality of ingredients, choice of vehicle, and proper use of additives.